Product Information
- Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2
- H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2
- (2S)-2-[(2-aminoacetyl)amino]-N-[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S,2R)-1-[[2-[[(1S)-2-[[1-benzyl-2-[[(1S)-1-carbamoyl-3-methylsulfanyl-propyl]amino]-2-oxo-ethyl]amino]-1-(3H-imidazol-4-ylmethyl)-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]amino]-1-methyl-2-oxo-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]butanediamide
Neuromedin C (NMC) is a peptide that belongs to the family of neuromedin and is a potent activator of ion channels. It has been shown to be a ligand for opioid receptors, which may be due to its ability to inhibit the release of neurotransmitters such as acetylcholine and noradrenaline. Neuromedin C has also been shown to inhibit the binding of morphine-6 beta-glucuronide in rat brain synaptosomes. In addition, NMC has been reported as an inhibitor of cell proliferation and induce apoptosis in various cancer cells including colon and prostate cancers.
Neuromedin C is a potent activator of ion channels that can bind with opioid receptors. It inhibits the release of neurotransmitters such as acetylcholine and noradrenaline and also inhibits binding with morphine-6 beta-glucuronide in rat brain synaptosomes. Furthermore, it induces apoptosis
Chemical properties
Technical inquiry about: 3D-PNM-4153-V Neuromedin C (Human, Porcine, Canine)
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