17β-Estradiol 3-β-D-glucuronide

CAS: 15270-30-1

Ref. 3D-QAA27030

Product Information

• Name: 17β-Estradiol 3-β-D-glucuronide
• Synonyms: (17beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid, (17β)-17-Hydroxyestra-1,3,5(10)-trien-3-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, (8xi,9xi,14xi,17beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronic acid, 17alpha-Estradiol-3-glucuronide, 17β-Estradiol 3-glucosiduronate, 17β-Estradiol 3-glucuronide, Estradiol 3-glucosiduronate, Estradiol-17β-3-(β-<span class="text-smallcaps">D</span>-glucuronide), Estrane, β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv., Glucopyranosiduronic acid, 17β-hydroxyestra-1,3,5(10)-trien-3-yl, β-<span class="text-smallcaps">D</span>-, beta-D-Glucopyranosiduronic acid, (17beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl-, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl, β-<span class="text-smallcaps">D</span>-Glucosiduronic acid, 17β-hydroxyestra-1,3,5(10)-trien-3-yl

Description

17β-Estradiol 3-β-D-glucuronide is a metabolite of estradiol that is formed in the liver. It has been shown to have a high affinity for the estrogen receptor and can be used as a marker for chronic exposure to estradiol. 17β-Estradiol 3-β-D-glucuronide has also been shown to inhibit protein synthesis in mammalian cells by blocking the activity of the protein polymerase, which is required for cell division. This compound also binds to toll-like receptor 4 (TLR4), which may be due to its ability to induce cytokine production.

• Brand: Biosynth

Chemical properties

• Molecular weight: 448.5 g/mol
• Formula: C₂₄H₃₂O₈
• Purity: Min. 95%