Product Information
Quinazolone is a quinazoline derivative with a 2-amino-4H-3,1-benzoxazin-4-one moiety. It is an inhibitor of enzymes that catalyze the phosphorylation of alkenes and alkynes, such as malonate decarboxylase and acetoacetyl-CoA thiolase. Quinazolones are also used in pharmaceuticals, mainly as anticonvulsants or antipsychotics. The quinazolone group is obtained by condensation of cyanamide with diethyl malonate or ethyl malonate. The resulting quinazoline can be converted to the corresponding quinazolone by replacement of the amino group with an amine. This reaction is called the Baeyer-Villiger oxidation. Quinazolones can also be synthesized from aralkyl chlorides by treatment with phenylurea followed by hydrolysis
Chemical properties
Technical inquiry about: 3D-QAA60711 2-Amino-4H-3,1-benzoxazin-4-one
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