Product Information
- Estra-1,3,5(10)-Triene-3,17-Diol, 2-Bromo-
- 2-Bromoestra-1(10),2,4-Triene-3,17-Diol
2-Bromo 17β-estradiol is a synthetic estrogen that is used for the treatment of breast cancer. This drug binds to the estrogen receptor, which alters the expression of genes, leading to apoptosis and inhibition of cell proliferation in tissues. 2-Bromo 17β-estradiol has been shown to be more potent than estradiol benzoate (EB) in inhibiting the growth of rat liver microsomes and MCF-7 cells. This drug also leads to an increase in kinetic data and enzyme activities in vitro. The modification of estrogen with bromine may be responsible for its increased potency over EB.
Chemical properties
Technical inquiry about: 3D-QAA83307 2-Bromo 17β-estradiol
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