3-(Aminomethyl)benzo[b]thiophene

CAS: 40615-04-1

Ref. 3D-QBA61504

Product Information

• Name: 3-(Aminomethyl)benzo[b]thiophene
• Synonyms: 1-Benzothiophene-3-Ylmethylamine, Benzothiophene-3-Methylamine, Benzo[B]Thiophen-3-Ylmethylamine, Benzothiophen-3-Ylmethanamine
• CAS: 40615-04-1

Description

3-(Aminomethyl)benzo[b]thiophene is a chemical compound that belongs to the class of reductive amination. This chemical reacts through reductive alkylation with aldehydes and ketones to yield the corresponding 3-substituted benzothiophenes. Mechanistically, this reaction proceeds by initial formation of the imine followed by reduction of the carbonyl group. The reductive amination is catalyzed by an acid or base catalyst in presence of a reducing agent. Reduction of the carbonyl group yields an alcohol, which reacts with ammonia to form an amine.

3-(Aminomethyl)benzo[b]thiophene can also be obtained from cyclized benzenemethanol derivatives, such as 3-aminobenzoic acid (3-AA). Reaction of 3-AA with methyl bromoacetate produces 3-methylbenzoic acid methyl ester

• Brand: Biosynth

Chemical properties

• Molecular weight: 163.23 g/mol
• Formula: C₉H₉NS
• Purity: Min. 95%