Product Information
- (3-Bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
- 2-[(3-Bromo-4-Hydroxy-5-Tert-Butyl-Phenyl)Methylidene]Propanedinitrile
- Propanedinitrile, [[3-Bromo-5-(1,1-Dimethylethyl)-4-Hydroxyphenyl]Methylene]-
- Propanedinitrile, 2-[[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-
AG 1024 is a potent inhibitor of the IGF-1R kinase. It has been shown to inhibit tumor growth and induce apoptosis in cancer cells. AG 1024 also inhibits the phosphorylation of IGF-1R, which prevents the activation of downstream signaling pathways, such as phosphatidylinositol 3-kinase (PI3K) and protein kinase B (AKT). AG 1024 also displays inhibitory properties on the polymerase chain reaction (PCR) amplification process. AG 1024 can be used to diagnose bowel disease or resistant breast cancer.
Chemical properties
Technical inquiry about: 3D-QCA67807 AG 1024
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