5-Chloro-8-hydroxyquinoline-7-carbaldehyde
CAS: 90876-69-0
Ref. 3D-QDA87669
50mg | To inquire | ||
500mg | To inquire |
Product Information
5-Chloro-8-hydroxyquinoline-7-carbaldehyde (5C8HQ) is an inhibitor of matrix metalloproteinases (MMPs). It is a potent inhibitor of MMP-2, with IC50 values of 0.037 μM in A549 cells and 0.03 μM in human erythrocytes. 5C8HQ has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. 5C8HQ binds to the active site of MMPs, preventing them from degrading collagen and other extracellular matrix proteins, leading to cell death by apoptosis.
Chemical properties
Technical inquiry about: 3D-QDA87669 5-Chloro-8-hydroxyquinoline-7-carbaldehyde
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