Product Information
- 1-Naphthol,3-amino- (7CI)
3-Aminonaphthalen-1-ol is a hydrolysis product of the drug chloroquine. It has been shown to have antimalarial activity. 3-Aminonaphthalen-1-ol binds to nuclear, chloride, and carboxyamide groups in the parasite's cell membrane, which disrupts ion transport and causes an influx of chloride ions into the cells. This leads to plasmolysis (the collapse of cytoplasmic contents) and cytotoxicity. The thionyl group is hydrolyzed by 3-aminonaphthalen-1-ol, leading to the release of hydrogen sulfide gas. Hydrogen sulfide gas is toxic for red blood cells and can cause hemolysis (the rupture of red blood cells).
Chemical properties
Technical inquiry about: 3D-QDA92379 3-Aminonaphthalen-1-ol
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
