Product Information
Tert-butyl 6-chloronicotinate is a chemical compound that is used as a reagent in organic synthesis. It is prepared by reacting tert-butyl nitrite with chloroform. This transformation can be achieved efficiently within 10 minutes and the yield of the reaction can be increased by using azide instead of ammonium chloride. The tert-butyl group on the compound provides an efficient method for amine displacement, which is useful for heteroaryl substitution. The reaction has been shown to work well with amines such as pyridine, quinoline, and indole.
Chemical properties
Technical inquiry about: 3D-QEA30957 tert-Butyl 6-chloronicotinate
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