Product Information
- 1,2-Diethyl-3-hydroxy-4(1H)-pyridinone
- CP94
- CGP 46700
- 4(1H)-Pyridinone, 1,2-diethyl-3-hydroxy-
- 1,2-diethyl-3-hydroxypyridin-4(1H)-one
1,2-Diethyl-3-hydroxypyridin-4-one (1,2DH) is a ligand that can bind to the HIF-1α protein and inhibit its activity. It has been shown to induce autophagy in cells exposed to hypoxia. 1,2DH is also an endomembrane molecule that modulates cancer autophagy and modulates angiogenesis. This compound is a hydroxylase inhibitor that inhibits the production of reactive oxygen species by converting hydrogen peroxide into water. It also prevents proteasomal degradation of proteins and modulates cancer cell proliferation by inhibiting the transcription factor HIF-1α.
Chemical properties
Technical inquiry about: 3D-QEA90075 1,2-Diethyl-3-hydroxypyridin-4-one
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