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Product Information
- 4-Acetamido-4-Hydroxy-2-Butenoicacidgamma-Lactone
- 4-Acetamido-4-hydroxy-2-butenoic acid γ-lactone
- 5-Acetamido-2-Furanone
- Acetamide, N-(2,5-dihydro-5-oxo-2-furanyl)-
- Acetamide, N-(2,5-dihydro-5-oxo-2-furyl)-
- N-(2,5-Dihydro-5-oxo-2-furanyl)acetamide
- N-(5-oxo-2,5-dihydrofuran-2-yl)acetamide
- NSC 114350
5-Acetamido-2[5H]-furanone is a chemical that is used to treat zearalenone-induced reproductive toxicity. 5-Acetamido-2[5H]-furanone enhances the responsiveness of animals to estradiol, and represses TNF-α expression in the intestine. The effect of 5-acetamido-2[5H]-furanone on the development of intestinal inflammation has been studied in humans and animals. In humans, 5-acetamido-2[5H]-furanone reduces proinflammatory cytokines such as TNF-α and IL1β, which are induced by zearalenone. This drug also reverses intestinal damage caused by zearalenone in animals. Combination therapy with 5-acetamido-2[5H]-furanone and other drugs may be useful for treating inflammatory bowel disease (IBD) or IBS.
Chemical properties
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