(S)-(-)-N,N-Dimethyl-1-phenylethylamine

CAS: 17279-31-1

Ref. 3D-SAA27931

Product Information

• Name: (S)-(-)-N,N-Dimethyl-1-phenylethylamine
• Synonyms: (1S)-N,N-dimethyl-1-phenylethanamine, (1S)-N,N-dimethyl-1-phenylethanaminium, (S)(-)-N,N-Dimethyl-Alpha-Phenethylamine, (S)-(-)-Alpha-Methyl-N,N-Dimethylbenzylamine, (S)-(-)-Alpha-N,N-Trimethylbenzylamine, (S)-(-)-N,N-Dimethyl-1-Phenethylamine, 9 7%, (S)-(-)-N,N-Dimethyl-1-Phenylethylamine, (S)-N,N,α-Trimethylbenzenemethanamine, (S)-[1-(Dimethylamino)ethyl]benzene, (αS)-N,N,α-Trimethylbenzenemethanamine, Alpha,N,N-Trimethylbenzylamine, Benzenemethanamine, N,N,α-trimethyl-, (S)-, Benzenemethanamine, N,N,α-trimethyl-, (αS)-, Benzylamine, N,N,α-trimethyl-, (S)-(-)-, Dimethyl((S)-1-phenylethyl)amine, S(-)-N,N,Alpha-Trimethylbenzylamine

Description

(S)-(-)-N,N-Dimethyl-1-phenylethylamine is a ligand that binds to the active site of proton pumps in the stomach and inhibits acid secretion. It has been shown to be effective against gastric ulcers caused by H. pylori infection and also prevents the formation of esophageal ulcers induced by reflux esophagitis. The asymmetric synthesis of (S)-(-)-N,N-dimethyl-1-phenylethylamine was achieved through a palladium complexation with phenylphosphine. This molecule is an amine ligand that has been shown to have a high affinity for nucleophilic sites on the surface of proton pumps in the stomach. The x-ray crystal structure of this molecule bound to an ESI fragment of proton pump shows that it forms hydrogen bonds with amino acids at the active site. The ligand is unsymmetrical because it contains two different

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.24 g/mol
• Formula: C₁₀H₁₅N
• Purity: Min. 95%