Ala-pNA

CAS: 1668-13-9

Ref. 3D-SAN-3068

Product Information

• Name: Ala-pNA
• Synonyms: (2S)-2-Amino-N-(4-nitrophenyl)propanamide, 2-Amino-4′-nitro-<span class="text-smallcaps">L</span>-propionanilide, <span class="text-smallcaps">L</span>-Alanine 4-nitroanilide, <span class="text-smallcaps">L</span>-Alanine p-nitroanilide, <span class="text-smallcaps">L</span>-Alanyl p-nitroanilide, Ala-4-nitroanilide, Alanine-4-nitroanilide, Alanine-p-nitroanilide, L-Alanine-4-nitroanilide, N-(4-nitrophenyl)-L-alaninamide, N-α-<span class="text-smallcaps">L</span>-Alanine p-nitroanilide, Propanamide, 2-amino-N-(4-nitrophenyl)-, (2S)-, Propanamide, 2-amino-N-(4-nitrophenyl)-, (S)-, Propionanilide, 2-amino-4′-nitro-, <span class="text-smallcaps">L</span>-
• CAS: 1668-13-9

Description

Ala-pNA is a peptide hormone that is related to vasopressin and has been shown to be a potential drug target for renal cell cancer. In vitro studies have shown that Ala-pNA inhibits the growth of human leukemia cells and other carcinoma cell lines. The reduction in cell proliferation was due to the decrease in proteolytic activity, which was due to the inhibition of collagenase synthesis. This peptide hormone also inhibits protein synthesis, leading to decreased production of enzymes such as p-nitrophenyl phosphate synthase and sodium citrate synthase. A study on the use of this compound on rats with induced renal carcinoma showed that it had no toxicological effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 209.2 g/mol
• Formula: C₉H₁₁N₃O₃
• Purity: Min. 95%