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[Nphe1]Nociceptin(1-13)NH2
CAS: 267234-08-2
Ref. 3D-SKA23408
| 5mg | 1,505.00 € | ||
| 10mg | 2,408.00 € | ||
| 25mg | 4,514.00 € | ||
| 50mg | 7,222.00 € |
Product Information
Nociceptin is a neuropeptide of the tachykinin family that is primarily expressed in the brain. It has been shown to have an important role in long-term treatment of depression and pain. Nociceptin is a bifunctional molecule with both antinociceptive and excitatory effects. Its analgesic properties are mediated by its ability to inhibit the release of substance P and calcitonin gene-related peptide, which are neurotransmitters involved in pain transmission. Nociceptin also has excitatory effects on tissues such as the stomach, pancreas, heart, and bladder. It may also be able to reduce inflammation by inhibiting histamine release from mast cells.
Nphe1]Nociceptin(1-13)NH2 has been shown to be effective in chronic pain models including those induced by nerve injury and chemotherapy-induced peripheral neuropathy. The activation of nociceptin receptors leads to inhibition
Chemical properties
Technical inquiry about: 3D-SKA23408 [Nphe1]Nociceptin(1-13)NH2
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