Canertinib (CI-1033)

CAS: 267243-28-7

Ref. 3D-SKA24328

Product Information

• Name: Canertinib (CI-1033)
• Synonyms: 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, 4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline, Canertinib base, Cl 1033, N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide, N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[2-(morpholin-4-yl)ethoxy]quinazolin-6-yl}prop-2-enamide, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Description

Canertinib is a small molecule that inhibits the protein synthesis of cancer cells by inhibiting the epidermal growth factor receptor (EGFR). It has been shown to have therapeutic effects against lung, brain, and breast cancers. Canertinib also binds to the EGFR monoclonal antibodies, which are used in cancer immunotherapy. This drug has been shown to inhibit the growth of human osteosarcoma cells in vitro and in vivo. Canertinib has also been shown to inhibit fatty acid synthesis and cell signaling pathways that regulate cancer cell growth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 485.94 g/mol
• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: Min. 95%