10-(3-Chlorophenyl)-7-nitropyrimido(4,5-B)quinoline-2,4(3H,10H)-dione
CAS: 317326-90-2
Ref. 3D-SMA32690
1mg | Discontinued | ||
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued |
Product Information
10-(3-Chlorophenyl)-7-nitropyrimido(4,5-B)quinoline-2,4(3H,10H)-dione is a pyridopyrimidine derivative which inhibits the activity of the protein tyrosine phosphatase 1B (PTP1B). PTP1B is a negative regulator of insulin signaling and has been implicated in diabetes and obesity. 10-(3-Chlorophenyl)-7-nitropyrimido(4,5-B)quinoline-2,4(3H,10H)-dione has been used as a research tool to study the function of PTP1B and may be useful as an inhibitor in diabetes treatment.