Product Information
8-Bromo-2-chloroquinoxaline is a potent and selective Jak2 inhibitor. It has been shown to inhibit the activity of phosphorylated JAK2 in vitro and in vivo, which is important for the development of inflammatory diseases. 8-Bromo-2-chloroquinoxaline has pharmacokinetic properties that are favorable for oral administration, which suggests it may be useful as a therapeutic agent. 8-Bromo-2-chloroquinoxaline has a class of inhibitors that are low nanomolar to nanomolar with high potency. This class includes compounds such as imatinib, sunitinib, sorafenib, vemurafenib, and pazopanib.
Chemical properties
Technical inquiry about: 3D-STB50067 8-Bromo-2-chloroquinoxaline
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