(R)-(-)-NBD-APy [=(R)-(-)-4-Nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination]

CAS: 143112-51-0

Ref. 3D-TFA11251

Product Information

• Name: (R)-(-)-NBD-APy [=(R)-(-)-4-Nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination]
• Synonyms: (+)-4-Nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole, (3R)-1-(4-nitro-2,1,3-benzoxadiazol-7-yl)pyrrolidin-3-amine, (3R)-1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-3-pyrrolidinamine, (R)-(-)-1-(7-Nitro-4-Benzofurazanyl)-3-Pyrrolidinamine, (R)-(-)-4-(3-Aminopyrrolidino)-7-Nitrobenzofurazan, (R)-(-)-4-Nitro-7-(3-Aminopyrrolidin-1-Yl)-2,1,3-Benzoxadiazole, (R)-(-)-4-Nitro-7-(3-Aminopyrrolidin-1-Yl)Benzofurazan, (R)-(-)-Nbd-Apy [=(R)-(-)-4-Nitro-7-(3-Aminopyrrolidin-1-Yl)-2,1,3-Benzoxadiazole], 2,1,3-Benzoxadiazole, 3-pyrrolidinamine deriv., 3-Pyrrolidinamine, 1-(7-nitro-2,1,3-benzoxadiazol-4-yl)-, (3R)-, 3-Pyrrolidinamine, 1-(7-nitro-2,1,3-benzoxadiazol-4-yl)-, (R)-, 3-Pyrrolidinamine, 1-(7-nitro-4-benzofurazanyl)-, (R)-, HPLClabelingreagentfore.e.determ
• CAS: 143112-51-0

Description

(R)-(-)-NBD-APy is an experimental reagent that is used to determine the enantiomeric composition of racemic amines. It contains a cavity with two beta-cyclodextrins, which are diastereomers. The chiral selector (4-nitrobenzoxadiazole) is attached to one of the beta-cyclodextrin molecules and the other beta-cyclodextrin molecule has a hydrogen atom in its cavity. The chiral selector provides two different geometries for the alpha carbon atom. This difference in geometry causes different levels of fluorescence for each stereoisomer, making it possible to determine the enantiomeric composition by measuring the fluorescence intensity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 249.23 g/mol
• Formula: C₁₀H₁₁N₅O₃
• Purity: Min. 95%