Product Information
JNJ-38877618(OMO-1) is a novel synthetase inhibitor that has been shown to have potent anti-tumor activity in vitro and in vivo. This drug selectively inhibits the synthesis of siderophores by the iron transporter, ferric reductase, and is also effective against neutrophil chemotaxis. JNJ-38877618(OMO-1) has a low bioavailability and poor solubility, which limits its use as an oral drug. However, it has been shown to be safe when used at high doses in mice. The safety profile of this drug is yet to be determined during clinical development.
Chemical properties
Technical inquiry about: 3D-TMB54074 JNJ-38877618(OMO-1)
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