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4-amino-2-chloronicotinic acid
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4-amino-2-chloronicotinic acid

CAS: 1018678-38-0

Ref. 3D-TQB67838

50mg
177.00 €
500mg
666.00 €
Estimated delivery in United States, on Tuesday 7 Jan 2025

Product Information

Name:
4-amino-2-chloronicotinic acid
Synonyms:
  • 3-Pyridinecarboxylic acid, 4-amino-2-chloro-
  • 2-Chloro-4-aminonicotinic acid
  • 4-Amino-2-chloro-3-pyridinecarboxylic acid
Description:

4-Amino-2-chloronicotinic acid is a nitrogenous organic compound. It is a synthetic molecule that can be used as a substrate for the chemical reactions of pyrimidine compounds, such as nucleosides and nucleotides, and it has been used as a lead structure in the design of drugs that inhibit tyrosine kinase. The synthesis of this compound involves the reaction of 4-aminoquinoline with chloroacetic acid. This synthetic process has been optimized to produce high yields and purity levels. The calcium-sensing receptor (CaSR) is an important regulator of parathyroid function, which in turn regulates calcium homeostasis in the body. A number of heterocycles have been synthesized and tested as CaSR inhibitors, with 4-amino-2-chloronicotinic acid being one of them. In vitro studies have shown that this compound inhibits CaSR activity at picomolar concentrations.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
172.57 g/mol
Formula:
C6H5ClN2O2
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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