Bakkenolide A

CAS: 19906-72-0

Ref. 3D-UAA90672

Product Information

• Name: Bakkenolide A
• Synonyms: (2′R,3′aR,4′S,7′aR)-Decahydro-3′a,4′-dimethyl-4-methylenespiro[furan-3(2H),2′-[2H]inden]-2-one, (3R,3a'R,4'S,7a'R)-3a',4'-dimethyl-4-methylidenedecahydrospiro[furan-3,2'-inden]-2-one, 3A',4'-Dimethyl-4-Methylidenedecahydrospiro[Furan-3,2'-Inden]-2-One, Bakkenolid A, Fukinanolid, Fukinanolide, Nsc 292655, Spiro(furan-3(2H),2'-(2H)inden)-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'R-(2'alpha,3'aalpha,4'alpha,7'aalpha))- (9CI), Spiro(furan-3(2H),2'-indan)-2-one, 3'a,4,4',5,5',6',7',7'abeta-octahydro-3'abeta,4'beta-dimethyl-4-methylene-, (2'R)- (8CI), Spiro[furan-3(2H),2′-[2H]inden]-2-one, decahydro-3′a,4′-dimethyl-4-methylene-, (2′R,3′aR,4′S,7′aR)-, Spiro[furan-3(2H),2′-[2H]inden]-2-one, decahydro-3′a,4′-dimethyl-4-methylene-, [2′R-(2′α,3′aα,4′α,7′aα)]-, Spiro[furan-3(2H),2′-indan]-2-one, 3′a,4,4′,5,5′,6′,7′,7′aβ-octahydro-3′aβ,4′β-dimethyl-4-methylene-, (2′R)-
• CAS: 19906-72-0

Description

Bakkenolide A is a natural compound that has been extracted from an acetate extract of the fungus Aspergillus bakkeni. Bakkenolide A has shown to have cytotoxic effects on k562 cells, which are human leukemia cells. Bakkenolide A inhibits neuronal death by blocking the release of glutamate and aspartate in the brain. It also inhibits the production of pro-inflammatory cytokines and chemokines in cultured microglia. The biological activity of this compound has been investigated using a surface methodology and LC-MS/MS method. Bakkenolide A is chiral, so it is important to use a chiral analytical method when studying this compound.

• Brand: Biosynth

Chemical properties

• Molecular weight: 234.33 g/mol
• Formula: C₁₅H₂₂O₂
• Purity: Min. 95%