2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
CAS: 19983-15-4
Ref. 3D-UAA98315
| 50mg | 175.00 € | ||
| 500mg | 653.00 € |
Product Information
- 2-Thiazoline-4-carboxylic acid, 2-phenyl-
- 4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid
- 2-Phenyl-2-thiazoline-4-carboxylic acid
- 4-Thiazolecarboxylic acid, 4,5-dihydro-2-phenyl-
2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid is an intermediate in the biosynthesis of flavoproteins. It is synthesized by a nonribosomal peptide synthetase (NRPS) and then converted to an active form of the enzyme by excision of the thiazole moiety. This conversion is catalyzed by a flavoprotein. The reaction proceeds via oxidative hydrogenation reactions, which are catalysed by a cytochrome P450 reductase and NADPH. 2-Phenyl-4,5-dihydro-1,3-thiazole-4 carboxylic acid has been shown to be effective in vitro as an inhibitor of bleomycin hydrolase activity and as an inhibitor of hydrogenation reactions that produce hydrogen peroxide from hydroperoxides.
Chemical properties
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