2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-yl)propane-1,3-diol
CAS: 1220973-37-4
Ref. 3D-VYB97337
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Product Information
2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-yl)propane-1,3-diol is a potent and selective inhibitor of protein interactions. 2DAPB binds to the active site of the enzyme adenylyl cyclase (AC), inhibiting the generation of cAMP. This inhibition leads to decreased signaling through Gs proteins and increased signaling through Gi proteins. 2DAPB has been shown to inhibit the binding of acetylcholine to the muscarinic receptor M1 in vitro with an IC50 value of 0.6 μM.
2DAPB has also been shown to be more potent than atropine in inhibiting binding of acetylcholine to muscarinic receptors, but less potent than hexamethonium in inhibiting binding of acetyl
Chemical properties
Technical inquiry about: 3D-VYB97337 2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-yl)propane-1,3-diol
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