PNU112455A hydrochloride
CAS: 21886-12-4
Ref. 3D-WAA88612
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
PNU112455A hydrochloride
Description:
PNU112455A hydrochloride is a small-molecule growth factor that is a potent inhibitor of the CDK4/6 enzyme. PNU112455A hydrochloride binds to and dephosphorylates CDK4/6, which inhibits the phosphorylation of Rb by cyclin E and prevents the transition from G1 to S phase in cells. PNU112455A hydrochloride has been shown to inhibit growth in cancer cells such as MDA-MB-231 breast cancer cells, epidermal growth factor receptor (EGFR), and miapaca-2 cells. It appears to have a cell-specific apoptotic effect.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
301.75 g/mol
Formula:
C10H12ClN5O2S
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
