Product Information
- 3-Quinolinecarbonitrile, 1,4-Dihydro-4-Oxo-
- 3-Quinolinecarbonitrile, 4-Hydroxy-
- 4-Hydroxychinolin-3-carbonitril
- 4-Hydroxyquinoline-3-carbonitrile
- 4-Oxo-1,4-dihydrochinolin-3-carbonitril
4-oxo-1,4-Dihydroquinoline-3-carbonitrile (4ODQ) is a synthetic compound that is acidic in nature. It hydrolyzes in acidic conditions to form a carboxylic acid and ammonia. 4ODQ can also react with amines to form azides, chloride to form chloramines, methyl anthranilate to form piperidines, trifluoride to form triflates, and morpholine to form morpholines. The chemical structure of 4ODQ consists of an anthranilate moiety which has been decarboxylated and an amine group which has been enaminated.
4ODQ inhibits the growth of cancer cells by binding to the ATP binding site on the enzyme kinase B (BRAF), thereby preventing phosphorylation of downstream proteins that are involved in cell proliferation. This inhibition leads to apoptosis or programmed cell death.
Chemical properties
Technical inquiry about: 3D-WCA08359 4-oxo-1,4-Dihydroquinoline-3-carbonitrile
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