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Benzeneacetic acid, 4-(methoxycarbonyl)-2-propyn-1-yl-, methyl ester
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Benzeneacetic acid, 4-(methoxycarbonyl)-2-propyn-1-yl-, methyl ester

CAS: 146464-90-6

Ref. 3D-WFA46490

25mgDiscontinued
50mgDiscontinued
100mgDiscontinued
250mgDiscontinued
500mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
Benzeneacetic acid, 4-(methoxycarbonyl)-2-propyn-1-yl-, methyl ester
Synonyms:
  • 4-(Methoxycarbonyl)-α-2-propyn-1-ylbenzeneacetic acid methyl ester
  • 4-(Methoxycarbonyl)-Alpha-Propargylphenyl-Acetic Acid Methyl Ester
  • Α-Propargylhomoterephthalic Acid Dimethyl Ester
Description:

Benzeneacetic acid, 4-(methoxycarbonyl)-2-propyn-1-yl-, methyl ester is a cytotoxic compound that has been shown to exhibit antitumor activity. It is a prodrug of pralatrexate, which can be hydrolyzed by esterases or glucuronidases to the active form. The active form exhibits cytotoxicity against tumours and is effective in killing cells with low levels of glutathione. Pralatrexate has been shown to have an inhibitory effect on the growth of leukemic cells.

Benzeneacetic acid, 4-(methoxycarbonyl)-2-propyn-1-yl-, methyl ester is a secondary metabolite produced by Streptomyces sp. It inhibits the enzyme dihydrofolate reductase and affects DNA synthesis and repair by inhibiting thymidylate synthase and dTMP kinase activities

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
246.26 g/mol
Formula:
C14H14O4
Purity:
Min. 95%
MDL:
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Concentration:
EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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