Product Information
- (2S)-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
- (αS)-α-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid
- Benzenepropanoic acid, α-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (S)-
- Benzenepropanoic acid, α-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αS)-
- Hmr-4005
- Lu-135252
Darusentan is a drug that is used to treat chronic heart failure. It is a selective endothelin receptor antagonist, which blocks the binding of endothelin-1 to the receptor and prevents the activation of the receptor. This drug has been shown to be beneficial for patients with congestive heart failure who are not on β-blockers. Darusentan has been shown to reduce systolic pressure in these patients, as well as improve cardiac function, kidney fibrosis and reverse experimental models of kidney disease.
Chemical properties
Technical inquiry about: 3D-WGA71484 Darusentan
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