Darusentan

CAS: 171714-84-4

Ref. 3D-WGA71484

Product Information

• Name: Darusentan
• Synonyms: (2S)-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid, (αS)-α-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid, Benzenepropanoic acid, α-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (S)-, Benzenepropanoic acid, α-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αS)-, Hmr-4005, Lu-135252
• CAS: 171714-84-4

Description

Darusentan is a drug that is used to treat chronic heart failure. It is a selective endothelin receptor antagonist, which blocks the binding of endothelin-1 to the receptor and prevents the activation of the receptor. This drug has been shown to be beneficial for patients with congestive heart failure who are not on β-blockers. Darusentan has been shown to reduce systolic pressure in these patients, as well as improve cardiac function, kidney fibrosis and reverse experimental models of kidney disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 410.42 g/mol
• Formula: C₂₂H₂₂N₂O₆
• Purity: Min. 95%