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((2,4-dichlorophenyl)sulfonyl)(isopropyl)(2-((isopropyl)amino)ethyl)amine
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((2,4-dichlorophenyl)sulfonyl)(isopropyl)(2-((isopropyl)amino)ethyl)amine

CAS: 946387-07-1

Ref. 3D-WMB38707

10mg
198.00 €
25mg
253.00 €
50mg
352.00 €
100mg
549.00 €
250mg
820.00 €
Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
((2,4-dichlorophenyl)sulfonyl)(isopropyl)(2-((isopropyl)amino)ethyl)amine
Synonyms:
  • 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
  • 2,4-Dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide
  • 946387-07-1
  • Ab 159908
  • Benzenesulfonamide, 2,4-dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]-
  • Gr Cg Dswny1& 1& 2My1& 1
  • Rn 1734
Description:

2,4-Dichlorophenylsulfonyl isopropyl (2-((isopropyl)amino)ethyl)amine ((2,4-DAPIS)) is a potent and selective inhibitor of the protein kinase PKCζ. It has been shown to be active in animal models of chronic cough and bronchial asthma. The 2,4-DAPIS binds to the ATP site on PKCζ and inhibits its activity by binding to the catalytic domain of the enzyme. Inhibition of PKCζ leads to decreased angiotensin system activity, which in turn decreases chronic cough and bronchial asthma. The 2,4-DAPIS also blocks potassium channels TRPV4, which may lead to an improvement of disease activity.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
353.31 g/mol
Formula:
C14H22Cl2N2O2S
Purity:
Min. 95%
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
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LQ:

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