Nilotinib N-oxide
CAS: 1246817-85-5
Ref. 3D-WZB81785
| 1mg | To inquire | |
| 2mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire |
Product Information
Nilotinib N-oxide is a bosutinib metabolite that is categorized as a profile 1B inhibitor. It has a chemical structure similar to imatinib and dasatinib. The metabolite of nilotinib N-oxide, which is an active form, focuses on the inhibition of chronic myeloid leukemia (CML) cells by targeting the oncoprotein BCR-ABL. Nilotinib N-oxide has been shown to have cardiac toxicity, which may be due to its ability to inhibit the synthesis of uridine and reduce thrombocytopenia. It also has the potential for toxicities such as pancreatitis and hepatotoxicity.
Chemical properties
Technical inquiry about: 3D-WZB81785 Nilotinib N-oxide
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