Etanidazole-D4

CAS: 22668-01-5

Ref. 3D-XAA66801

Product Information

• Name: Etanidazole-D4
• Synonyms: 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, Brn 0919296, Etanidazol, Etanidazol [Spanish], Etanidazole (SR-2508), Etanidazole [USAN:INN], Etanidazolum, Etanidazolum [Latin], Ethanidazole, Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, N-(2-Hydroxyethyl)-1-(2-nitro-1-imidazolyl)acetamide, N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide, N-(2-Hydroxyethyl)-2-nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide, NSC 301-467, Nsc 301467, Radinyl, Sr 2508, Unii-30Dka3Q1Hl

Description

Etanidazole (ETN) is a prodrug that is converted to the active form etanidazole-D4 in vivo. ETN has been shown to be effective as a cytotoxic agent against various types of tumor cells in vitro and in vivo. ETN has significant cytotoxicity against hypoxic cells, including acute toxicities caused by high doses of radiation or other agents. Etanidazole-D4 is an anti-cancer compound that has been shown to kill tumor cells through covalent linkages with DNA and cell nuclei, which causes the breakdown of the DNA backbone. Etanidazole-D4 also inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.

• Brand: Biosynth

Chemical properties

• Molecular weight: 218.2 g/mol
• Formula: C₇H₆D₄N₄O₄
• Purity: Min. 95%