Product Information
- 2-(TRIMETHYLSILYL)VINYLBROMIDE
- [(E)-2-Bromovinyl](trimethyl)silane
- Silane, [(E)-2-bromoethenyl]trimethyl-
- Silane, (2-bromoethenyl)trimethyl-
- (2-Bromovinyl)trimethylsilane
Alkenylsilane Cross-Coupling Agent
The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.
2-Bromovinyltrimethylsilane; 2-(Trimethylsilyl)vinylbromide
Contains 10-15% cis-isomerSlowly decomposes above 60 °C yielding ethyleneUseful for cross-coupling to 2-substituted vinylsilanesPotential for cross-coupling protocols to yield β-substituted vinylsilanesExtensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
