TRIETHYLSILYLTRIFLUOROMETHANESULFONATE

CAS: 79271-56-0

Ref. 3H-SIT8335.0

Product Information

• Name: TRIETHYLSILYLTRIFLUOROMETHANESULFONATE
• Synonyms: Methanesulfonic acid, 1,1,1-trifluoro-, triethylsilyl ester, Methanesulfonic acid, trifluoro-, triethylsilyl ester, TES-OTf, Triethylsilyl 1,1,1-trifluoromethanesulfonate, Triethylsilyl Trifluoromethanesulfonate, Triethylsilyl triflate, Triethylsilyl trifluoromethane sulphonate, Triethylsilyltrifluoromethanesulfonate, Trifluoromethanesulfonic acid triethylsilyl ester, Trifluoromethanesulphonic acid triethylsilyl ester
• CAS: 79271-56-0

Description

Trialkylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Triethylsilyltrifluoromethanesulfonate; TES-OTf; Triethylsilyltriflate; Triethylsilyl trifluoromethanesulphonate; Trifluoromethanesulfonic acid triethylsilyl ester
More reactive than SIT8250.0Useful for more hindered alcoholsUsed primarily for the protection of alcoholsCan be used to protect amines and carboxylic acidsSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

• Brand: Gelest

Chemical properties

• Molecular weight: 264.34
• Formula: C₇H₁₅F₃O₃SSi
• Color/Form: Straw Liquid