TRIMETHYLBROMOSILANE

CAS: 2857-97-8

Ref. 3H-SIT8430.0

Product Information

• Name: TRIMETHYLBROMOSILANE
• Synonyms: BROMOTRIMETHYLSILANE, Bromotrimetilsilano, Bromtrimethylsilan, Nsc 139857, Silane, bromotrimethyl-, TMS bromide, TMSBr, Trimethylbromosilane, Trimethylsilicon bromide, Trimethylsilyl bromide, bromotrimethyl-Silane
• CAS: 2857-97-8

Description

Trimethylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Trimethylbromosilane; Bromotrimethylsilane; Trimethylsilyl bromide; TMBS
More reactive than SIT8510.0 Less reactive, but more Less reactive, photolytically stable than SIT8564.0Nafion SAC-13 has been shown to be a recyclable catalyst for the trimethylsilylation of primary, secondary, and tertiary alcohols in excellent yields and short reaction timesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

• Brand: Gelest

Chemical properties

• Molecular weight: 153.09
• Formula: C₃H₉BrSi
• Purity: 97%
• Color/Form: Orange-Brown Liquid