Tacrolimus Monohydrate

CAS: 109581-93-3

Ref. AN-AG0035MN

Product Information

• Name: Tacrolimus Monohydrate
• Synonyms: [u'Anhydrous Tacrolimus', u'Anhydrous, Tacrolimus', u'FK 506', u'FK-506', u'FK506', u'FR 900506', u'FR-900506', u'FR900506', u'Prograf', u'Prograft', u'Tacrolimus', u'Tacrolimus Anhydrous', u'Tacrolimus, Anhydrous', u'Tacrolimus hydrate', u'109581-93-3', u'Prograf', u'Tsukubaenolide hydrate', u'UNII-WM0HAQ4WNM', u'Tacrolimus monohydrate; FK506', u'Astagraf XL', u'LCP-Tacro', u'WM0HAQ4WNM', u'Prograf (TN)', u'(-)-(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone monohydrate', u'(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-Dihydroxy- 3-{(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl}- 14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-15,19-epoxy- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro- 3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone monohydrate', u'(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone--water (1/1)', u'FK 506', u'FR900506', u'Tacrolimus [USAN:INN:BAN]', u'Protopic (TN)', u'Tacrolimus (USAN/INN)', u'Tacrolimus (FK-506)', u'Tacrolimus hydrate (JP17)', u'SCHEMBL317005', u'CHEMBL3989887', u'CHEBI:61057', u'AOB1673', u'NWJQLQGQZSIBAF-MLAUYUEBSA-N', u'C44H71NO13', u'(-)-(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-((E)-2-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone)monohydrate', u'EX-A2657', u'HY-13756A', u'AKOS015994743', u'CS-3076', u'KS-1245', u'RL00410', u'AN-33630', u'BC677061', u'FK-506 monohydrate, >=98% (HPLC)', u'AB0030445', u'X2641', u'D00107', u'EN300-220769', u'140497-EP2277565A2', u'140497-EP2277566A2', u'140497-EP2277567A1', u'140497-EP2277568A2', u'140497-EP2277569A2', u'140497-EP2277570A2', u'140497-EP2292280A1', u'Q-101412', u'Tacrolimus, United States Pharmacopeia (USP) Reference Standard', u'Tacrolimus, Pharmaceutical Secondary Standard; Certified Reference Material', u'Tacrolimus for system suitability, European Pharmacopoeia (EP) Reference Standard', u'tacrolimus', u'Protopic', u'FK-506 monohydrate', u'Tacrolimus [USAN]', u'Fk-506', u'C44H69NO12.H2O', u'MFCD11045918', u'CB12048', u'CID5282315', u'FR 900506', u'C44-H69-N-O12.H2-O', u'FR-900506', u'Tacrolimus monohydrate, 98% - 100MG 100mg', u'104987-11-3'], (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-prop-2-en-1-yl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone hydrate, 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, hydrate (1:1), (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-, 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-, 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-, 18-Tetramethyl-8-(2-Propenyl)-,Monohydrate,(3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*, 3-(2-(4-Hydroxy-3-Methoxycyclohexyl)-1-Methylethenyl)-14,16-Dimethoxy-9,10,12,Monohydrate, FK-506 Monohydrate, Tacforius, Tacrolimus hydrate, Tacrolimushydrate, Tsukubaenolide hydrate, Tsukubaenolidehydrate
• CAS: 109581-93-3
• Brand: Indagoo

Chemical properties

• Molecular weight: 822.0334
• Formula: C₄₄H₇₁NO₁₃
• Purity: 80%
• Color/Form: Solid
• InChI: InChI=1S/C44H69NO12.H2O/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7;/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3;1H2/b25-19+,27-21+;/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+;/m0./s1
• InChI key: NWJQLQGQZSIBAF-MLAUYUEBSA-N