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10-deacetylbaccatin III

CAS: 32981-86-5

Ref. BP-BP0011

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Estimated delivery in United States, on Wednesday 10 Jun 2020

Product Information

Name:
10-deacetylbaccatin III
Synonyms:
  • 10-DAB III; 10-Deacetylbaccatin III
Notes:

Can be supplied from milligrams to grams, up to kilograms.
Inquire for bulk scale, GMP is available on request.Except supply the 10-DAB III for R&D and reference standard, we also supply the 10-DAB III for intermediate of API, GMP is available on request.Profiles10-Deacetyl Baccatin III or 10-DAB III is a crucial intermediate for Paclitaxel & Docitaxel, two of the best anti-cancer drugs ever invented. Natural Paclitaxel was once isolated in very small quantities from the Yew tree (Taxus species) resulting in the large-scale destruction of its natural habitat. By extracting the pre-cursor 10-DAB III in large quantites from the Taxus baccata leaf, many subsequent semi-syntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and in the pharmacological profile of these important chemo-therapeutic agents.
analysis-method: HPLC-DAD
botanical-source: Taxus baccata; Taxus mairei SY Hu.
identification-method: Mass, NMR


Chemical properties

Molecular weight:
544.597
Formula:
C29H36O10
Purity:
98%

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