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Arctiin

CAS: 20362-31-6

Ref. BP-BP0187

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Estimated delivery in United States, on Monday 8 Jun 2020

Product Information

Name:
Arctiin
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Notes:

Arctigenin and arctiin have antiproliferative effect.[7]
Arctiin down-regulates cyclin D1 protein expression and that this at least partially contributes to the anti-proliferative effect of arctiin.[4]
Arctiin has ameliorative effects on glomerulonephritis is carried out mainly by suppression of NF-κB activation and nuclear translocation and the decreases in the levels of these pro-inflammatory cytokines, while SOD is involved in the inhibitory pathway of NF-κB activation; arctiin has favorable potency for the development of an inhibitory agent of NF-κB and further application to clinical treatment of glomerulonephritis, though clinical studies are required.[5]
Arctiin has been reported to have anti-inflammatory, anti-oxidant, antibacterial, and antiviral effects in vitro, it may exert anti-inflammatory effect by inhibiting the pro-inflammatory mediators through the inactivation of NF-kB.[2]
Arctiin induces an UVB protective effect in human dermal fibroblast cells through microRNA expression changes.[6]
Arctiin significantly induces cell detachment and decreases the cell numbers via the up-regulation of MUC-1 mRNA and protein in PC-3 cells.[3]
Arctiin, a lignan isolated from Arctium lappa (burdock) seeds, has a protective effect on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) -induced carcinogenesis particularly in the mammary gland in the promotion period, it may have a weak co-carcinogenic influence on MeIQx-induced hepatocarcinogenesis. [1]
Inquire for bulk scale.
The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Arctium lappa L.(Burdock).
identification-method: Mass, NMR
type-of-compound: Lignans


Chemical properties

Molecular weight:
534.558
Formula:
C27H34O11
Purity:
98%
Color/Form:
Powder

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