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Chrysophanol

Chrysophanol

CAS 481-74-3

Ref. BP-BP0348

20mg
100mg
1000mg
155.00 €
207.00 €
303.00 €
Estimated delivery time: ~13 days

Product Information

Name:
Chrysophanol
Synonyms:
  • Chrysophanic acid; 1,8-Dihydroxy-3-methylanthraquinone
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Notes:

Chrysophanol and physcion, are main active compounds of the plant Baill, has is active against plant powdery mildew, and physcion is much more bioactive than chrysophanol against these powdery mildews.[4]
Chrysophanol can inhibit NALP3 inflammasome activation and ameliorate cerebral ischemia/reperfusion in mice.[5]
Chrysophanol has anti-inflammatory activity through the suppression of NF-κB/caspase-1 activation in vitro and in vivo.[1]
Chrysophanol has mild cytotoxicity and anti-diabetic properties, it up to 100 microM exerts mild glucose transport activity and elevates the tyrosine phosphorylation of IR via tyrosine phosphatase 1B inhibition (IC50=79.86+/-0.12 microM), thus it could play metabolic roles in the insulin-stimulated glucose transport pathway.[3]
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.[2]
Inquire for bulk scale.
The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Cassia, Rumex, Rheum, sphodelus, Muehlenbeckia spp., Monilinia fructicola and others. V. widely distributed in plants and also found in the marine annelid Urechis unicinctus
identification-method: Mass, NMR
type-of-compound: Anthraquinones


Chemical properties

Molecular weight:
254.241
Formula:
C15H10O4
Purity:
98%
Color/Form:
Yellow powder

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