NFX1 rabbit pAb
Ref. EK-ES10386
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES10386 NFX1 rabbit pAb
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