Crk II (phospho Tyr221) rabbit pAb
Ref. EK-ES1448
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- CRK; Adapter molecule crk; Proto-oncogene c-Crk; p38
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES1448 Crk II (phospho Tyr221) rabbit pAb
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