IGF-I Receptor β (phospho-Tyr1135) rabbit pAb
Ref. EK-ES15515
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
Chemical properties
Technical inquiry about: EK-ES15515 IGF-I Receptor β (phospho-Tyr1135) rabbit pAb
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