TOP2A (Phospho Ser1213) rabbit pAb
Ref. EK-ES20165
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- DNA topoisomerase 2-alpha (EC 5.99.1.3;DNA topoisomerase II
- alpha isozyme)
catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.,miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.,PTM:Phosphorylation has no effect on catalytic activity.,similarity:Belongs to the type II topoisomerase family.,subcellular location:Generally located in the nucleoplasm.,subunit:Homodimer. Interacts with COPS5.,
Chemical properties
Technical inquiry about: EK-ES20165 TOP2A (Phospho Ser1213) rabbit pAb
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