Stat4 rabbit pAb
Ref. EK-ES3513
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- STAT4; Signal transducer and activator of transcription 4
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
Chemical properties
Technical inquiry about: EK-ES3513 Stat4 rabbit pAb
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