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Apaf-1 rabbit pAb

Ref. EK-ES4108

50µl
188.00 €
100µl
316.00 €
Estimated delivery in United States, on Monday 2 Dec 2024

Product Information

Name:
Apaf-1 rabbit pAb
Synonyms:
  • APAF1; KIAA0413; Apoptotic protease-activating factor 1; APAF-1
Description:

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
ELK Biotechnology
Long term storage:
Notes:

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Hazard Info

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Forbidden to fly:
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