GHR rabbit pAb
Ref. EK-ES4303
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011],
Chemical properties
Technical inquiry about: EK-ES4303 GHR rabbit pAb
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