Sclerostin rabbit pAb
Ref. EK-ES6491
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- SOST; Sclerostin
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES6491 Sclerostin rabbit pAb
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