Propantheline bromide

CAS: 50-34-0

Ref. TM-T1006

Product Information

• Name: Propantheline bromide
• Synonyms: Neopepulsan, Pro-Banthine, Neometantyl, (2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate, 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-, bromide, 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-, bromide (1:1), Ammonium, (2-hydroxyethyl)diisopropylmethyl-, bromide, xanthene-9-carboxylate, Corrigast, Diisopropyl(Methyl)(2-Xanthen-9-Ylcarbonyloxyethyl)Ammonium Bromide, Ercorax, Ercotina, Ketaman, Kivatin, L 113, L 113 (leveling agent), Neo-Metantyl, Neopepulsan, Pantas, Pantheline, Pervagal, Pro-Banthine, Pro-Gastron, Prodixamon, Propantel, Sc 3171, Xanthene-9-carboxylic acid, ester with (2-hydroxyethyl)diisopropylmethylammonium bromide, β-Diisopropylaminoethyl xanthene-9-carboxylate methobromide
• CAS: 50-34-0

Description

Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.

• Brand: Targetmol

Chemical properties

• Molecular weight: 448.4
• Formula: C₂₃H₃₀BrNO₃
• Purity: 98%