PF-915275
CAS: 857290-04-1
Ref. TM-T16510
1mg | 38.00 € | ||
2mg | 49.00 € | ||
5mg | 80.00 € | ||
10mg | 124.00 € | ||
25mg | 249.00 € | ||
50mg | 491.00 € | ||
100mg | 707.00 € | ||
500mg | 1,486.00 € | ||
1ml*10 (DMSO) | 88.00 € |
Product Information
- PF915275
- 4'-Cyanobiphenyl-4-Sulfonic Acid (6-Aminopyridin-2-Yl)Amide
- N-(6-aminopyridin-2-yl)-4'-cyanobiphenyl-4-sulfonamide
PF-915275 is an effective and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1, Ki = 2.3 nM, EC50 = 15 nM in vitro HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively.
Chemical properties
Technical inquiry about: TM-T16510 PF-915275
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