Product Information
Compound I-431, also known as SMARCA2/4-degrader-2, is a PROTAC degrader targeting SMARCA2 and SMARCA4. In A549 cells, it degrades SMARCA2/4 proteins with DC50s values of less than 100 nM and achieves a maximum degradation rate (Dmax%) exceeding 90% after a 24-hour treatment.
Chemical properties
Technical inquiry about: TM-T200532 PROTAC SMARCA2/4-degrader-2
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