α-(difluoromethyl)-DL-Arginine
CAS: 69955-43-7
Ref. TM-T35449
1mg | 79.00 € | ||
5mg | 197.00 € | ||
10mg | 320.00 € | ||
25mg | 474.00 € | ||
50mg | 687.00 € | ||
100mg | 917.00 € | ||
500mg | 1,838.00 € |
Product Information
- DFMA, RMI 71897, α-(difluoromethyl)-DL-Arginine
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, α-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models.
Chemical properties
Technical inquiry about: TM-T35449 α-(difluoromethyl)-DL-Arginine
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